Μηχανισμοί πρ
ό
κλ
η
σης Αθηροσκλ
ή
ρ
ω
σης στο
Μεταβολικό Σύνδρομο
Visceral obesity and the metabolic syndrome: a network of atherogenic factors. CRP= C-reactive protein; HDL-C= high-density lipoprotein cholesterol; IL-6= interleukin-6; LDL= low-density lipoprotein; PAI-1= plasminogen activator inhibitor-1; TNF-a= tumor necrosis factor-a.
Type 2 diabetes and
glycemic disorders
Dyslipidemia
•
Low serum HDL-C
•
Small, dense LDL particles
•
Hypertriglyceridemia
Hypertension
Impaired thrombolysis
•
PAI-1
Endothelial
dysfunction/inflammation
•
CRP
Microalbuminuria
Atherosclerosis
Visceral
obesity
Insulin
resistance
Free fatty
acids
TNF-a, IL-6
Reaven G. Drugs 1999;58(suppl):19-20